For pharma, biotech and academic groups
Bespoke computational pathology research. For questions that fall outside Precedent and Motif, such as a new tissue type, stain, disease area or endpoint, our scientific team designs and runs a scoped computational pathology study on your data, using the same tissue-language model.
The problem
Some questions do not fit a product
The question is new
Precedent and Motif answer defined questions in toxicology and clinical trials. A new tissue type, stain, disease area or endpoint may need a study designed around it.
Off-the-shelf tools address predefined tasks
Commercial image-analysis products are trained for defined tasks on defined tissues. If your question is not one of them, no product addresses it.
Building in-house is a multi-year programme
A pathology foundation model requires data engineering, self-supervised training capacity and pathology review. Most teams need the answer rather than the infrastructure.
How it works
A scoped study, start to finish
- 01
Scope and ingest
We agree the question, the cohort and the endpoints up front. Your whole-slide images are processed as they are, with no annotation step and no need to decide in advance what matters.
- 02
Map the cohort
The foundation model clusters your tissue into histomorphological phenotypes learned from the images themselves, giving every slide and every patient a phenotype composition.
- 03
Correlate and report
Phenotype composition is tested against your outcomes, omics or treatment response. You get the findings, the phenotypes behind them, and a clear account of what the data does and does not support.
Why this is different
The same engine as our products
TileBio Research studies run on the tissue-language model behind Precedent and Motif, so every finding rests on phenotypes a pathologist can open and inspect. Because the model learns tissue phenotypes without labels, a study can identify morphology that neither party set out to look for.
The deliverable
What you get
You get: a question and scope agreed in advance, analysis by our scientific team, and a written report of the findings with the phenotypes behind them.
Questions
Frequently asked
- What is TileBio Research?
- It is TileBio’s bespoke computational pathology offering. Our scientific team applies the label-free tissue-language model to your own whole-slide images to answer a question agreed in advance, and delivers a written report of the findings.
- When should we choose TileBio Research over Precedent or Motif?
- Choose Precedent for toxicology archives and studies, and Motif for response in clinical trial slides. TileBio Research is for everything else: questions where the design, data and deliverables need to be agreed case by case.
- What data do you need from us?
- Whole-slide images (H&E is the usual starting point), plus whatever outcome, treatment or molecular data you want the phenotypes correlated against. We can work with de-identified data under a data processing agreement, and we do not need any manual annotation.
- How large does the cohort need to be?
- Self-supervised learning benefits from scale, but a study does not need a population-scale cohort to be informative. At scoping we will advise whether your cohort can support the question you are asking.
- Who owns the results?
- Ownership of study outputs and any downstream rights are agreed in writing before work starts. We work on both a fee-for-service and a co-development basis, and will structure the study accordingly.
- How long does a study take?
- It depends on cohort size, data readiness and the number of endpoints. We give an indicative timeline at scoping, before any commitment.